Is there a size limit?

I exported a H264 MP4 file from Premiere. Its 4.5GB in size.
Smaller ones work fine but this one won't even load up.
I get a message saying its corrupted, in Quicktime, Media Player, and Sony Vegas. Even Premiere won't import it back in.

I tried exporting it twice. I'm convinced its not , in fact, corrupted, but a size issue.

Any comments?