Hi Josh,
After Effects does a LOT of different things. It's pretty accurate, I think, to compare it to photoshop. I'm sure someone on these forums will be able to help, but:
I haven't the slightest idea what you're trying to do.

Are you trying to make a "wall" of clips, for example four seperate videos playing simultaneously, each in its own quarter of the screen? Or are you trying to composite clips together, using transparencies, green-screening or other effects?
Please provide more info.