In my opinion the two (Premiere and Vegas) will both perform admirably well. The main difference between the two will be perception: one interface may be more suited to you than another for example. That said, the look and feel of Pro 2.0 is somewhat different to that of 6.5. Indeed Pro and 6.5 have no relationship whatsoever.
In terms of real time preview, both Vegas and Premiere Pro offer this without hardware acceleration. The difference with Premiere Pro plus hardware will be realtime (or harware acceleterated) MPEG output. That's a bonus.
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